Palermo have slipped to ninth in the Serie A table with 40 points from 29 matches and are nine points off the final Europa League slot.
The Rosanero have lost five league matches in a row, conceding 15 goals in the process.
Serse Cosmi’s side last scored on February 13 in their 4-2 home defeat to Fiorentina under Delio Rossi. Since then they have not scored in four matches.
The Aquile would be placed ninth in the table based on home form and 10th on their away record.
Palermo have scored 25 league goals at home and have conceded 21.
Milan are the current leaders of Serie A with 62 points from 29 matches, five ahead of second-placed Inter.
The Rossoneri have not won in their last couple of fixtures, having recorded a goalless draw with Tottenham Hotspur in London in the Champions League and then being held to a 1-1 draw by Bari at home last weekend.
Massimiliano Allegri’s side have the best defensive record in the Italian top flight this season, having shipped just 21 goals in 29 matches.
The Diavolo have the best away record in the championship, having collected 31 points in 14 matches on the road, losing just once.
Milan will be without striker Zlatan Ibrahimovic, who is suspended.
Prediction
Palermo are in a wretched run of form while Milan too seem to have had their confidence fractured after their exit from the Champions League. This could prove to be a cagey and somewhat awkward affair, although it also has the potential to be a thriller. Expected a scored draw.